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陳宇楓 助理教授

陳宇楓
陳宇楓 YU-FON CHEN
◆ 學　　歷：國立成功大學 生命科學系生物醫學組博士
◆ 電　　話：089-318855 分機6902
◆ 信　　箱：yfchen@nttu.edu.tw
◆ 專　　長：天然物與高分子活性分析、綠色生醫材料開發、藥物輸送系統、胺基酸藥物設計、發炎與癌症動物模式
◆ 開授課程：普通生物學、轉譯醫學、高等醫學微生物、生醫材料與生醫工程、高齡科技與應用【110學年度第2學期課表】

重要經歷
  • 國立臺東大學 生物醫學碩士學位學程 助理教授 
  • 輔英科技大學 醫學檢驗生物技術系 專案助理教授 
  • 國立中興大學 師資培育中心 兼任助理教授 
  • 國立成功大學 學生活動發展組 分子設計研究會 輔導老師 
  • 國立成功大學 化學工程學系 博士後研究員 
  • 國立成功大學 生物化學暨分子生物學研究所 博士後研究員 
  • 臺南科學工業區 亞洲基因科技股份有限公司 研發部 助理研究員 

 

證照
  • 專技高考醫事檢驗師及格
  • 中等學校教師資格檢定及格
  • Microsoft主題探索教材與網路學習社群 種子教師

 

期刊論文
  1. Chung FY, Lin YZ, Huang CR, Huang KW, Chen YF*. Crosslinking kiwifruit-derived DNA with natural aromatic aldehydes generates membranolytic antibacterial nanogels. International Journal of Biological Macromolecules. 2024, 255, 127947. (IF: 8.2, 5-Year IF: 7.8, ranking: 5/86 (5.81%) in Polymer Science).
  2. Zhuang HZ, Chen YF, Yu YC, Huang CR, Jiang YS, Chen CS, Jan JS. Gelatin Composite Gel Particles Comprised of In-Situ Formed Zinc Oxide and Silver Nanoparticles with Enhanced Antibacterial Activities Via Enzymatic Degradation. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2023, 132509. (IF: 5.2, 5-Year IF: 4.7, ranking: 58/161 (36.02%) in Chemistry, Physical).
  3. Chung FY, Huang CR, Chen CS, Chen YF*. Natural nanogels crosslinked with S-benzyl-L-cysteine exhibit potent antibacterial activity. Biomaterials Advances. 2023, 153, 213551. (IF: 7.9, 5-Year IF: 7.4, ranking: 7/54 (12.96%) in Materials Science, Biomaterials).
  4. Huang CR, Chang CH, Su YC, Tseng TJ, Chen YF*. Organic disulfide crosslinked nucleic acid-based nanocarriers for anticancer drug applications. Journal of Drug Delivery Science and Technology. 2023, 86, 104643. (IF: 5.062, 5-Year IF: 4.624, ranking: 48/361 (13.29%) in Pharmacology & Pharmacy).
  5. Chen YF, Wang ZH, Chen, YC, Chang CH, Zhuang HZ, Chung FY, Jan JS. Polypeptide Bilayer Assembly-Mediated Gene Delivery Enhances Chemotherapy in Cancer Cells. Molecular Pharmaceutics. 2023, 20, 1, 680–689. (IF: 5.364, 5-Year IF: 5.378, ranking: 36/361 (9.97%) in Pharmacology & Pharmacy).
  6. Chen YF, Yeh YT, Su YC, Liao CA, Huang CH, Cheng YJ, Jan JS. Cell adhesion inhibiting peptides exhibit potent anticancer activity and modulate intestinal microbiota. Materials & Design. 2022, 224, 111303. (IF: 9.417, 5-Year IF: 8.272, ranking: 52/414 (12.56%) in Materials Science, Multidisciplinary).
  7. Jan JS, Chang CH, Chen YF*. Application of DNA-Based Biomaterials as Carriers for Anticancer Strategies. Journal on Oncology. 2022, 2(2), 1041. (IF: 1.3, http://journalononcology.org/index.php)
  8. Chen YF, Lin WC, Wu CJ, Chang CH, and Jan JS. Effect of oil-water interface and payload-DNA interactions on payload-encapsulated DNA nanogels. Journal of Polymer Research 2022, 29, 8. (IF: 3.097, 5-Year IF: 2.599, ranking: 31/94 (32.97%) in Polymer Science)
  9. Hung YP, Chen YF, Tsai PJ, Huang IH, Ko WC, Jan JS. Advances in the application of nanomaterials in bacterial infectious diseases. Pharmaceutics 2021,13(11), 1913. (IF: 6.321, 5-Year IF: 6.734, ranking: 29/276 (10.51%) in Pharmacology & Pharmacy)
  10. Chen YF*, Chiou YH, Chen YC, Jiang YS, Lee TY, Jan JS. ZnO-loaded DNA nanogels as neutrophil extracellular trap-like structures in the treatment of mouse peritonitis. Materials Science and Engineering C 2021, 131, 112484. (IF: 7.328, 5-Year IF: 6.654, ranking: 7/41 (17.07%) in Materials Science, Biomaterials)
  11. Su CF, Chen YF, Tsai YJ, Weng SM and Jan JS. Antioxidant activity of linear and star-shaped polypeptides modified with dopamine and glutathione. European Polymer Journal 2021,152, 5,110497. (IF: 4.598, 5-Year IF: 4.674, ranking: 15/90 (16.7%) in Polymer Science)
  12. Chen YF, Chang CH, Hsu MW, Chang HM, Chen YC, Jiang YS and Jan JS. Peptide fibrillar assemblies exhibit membranolytic effects and anti-metastatic activity on lung cancer cells. Biomacromolecules 2020, 21, 9, 3836–3846. (IF: 6.092, 5-Year IF: 5.775, ranking: 5/89 (5.62%) in Polymer Science)
  13. Chen YF, Hsu MW, Su YC, Chang HM, Chang CH, Jan JS. Naturally derived DNA nanogels as pH- and glutathione-triggered anticancer drug carriers. Materials Science and Engineering C 2020, 114, 111025. (IF: 5.880, 5-Year IF: 5.364, ranking: 8/38 (21.1%) in Materials Science, Biomaterials)
  14. Tsai YC, Tang CC, Wu HH, Wang YS, Chen YF*. Antibacterial activity of cysteine-derived cationic dipeptides. Int J Pept Res Ther 2020, 26, 1107–1114.  (IF: 1.5, 5-Year IF: 1.381, ranking: 260/297 (87.54%) in Biochemistry & Molecular Biology)
  15. Chen IH, Chen YF, Liou JH, Laic JT, Hsu CC, Wang NY, Jan JS. Green synthesis of gold nanoparticle/gelatin/protein nanogels with enhanced bioluminescence/biofluorescence. Materials Science and Engineering C 2019, 105, 110101. (IF: 5.08, 5-Year IF: 4.628, ranking: 6/33 (18.2%) in Materials Science, Biomaterials)
  16. Chen YF, Lai YD, Chang CH, Tsai YC, Tang CC, Jan JS. Star-shaped polypeptides exhibit potent antibacterial activities. Nanoscale 2019, 11(24):11696-11708. (IF: 7.233, 5-Year IF: 7.713, ranking: 30/285 (10.52%) in Materials science & Multidisciplinary)
  17. Chen YF, Chang CH, Huang ZN, Su YC, Chang SJ, Jan JS. The JAK inhibitor antcin H exhibits direct anti-cancer activity while enhancing chemotherapy against LMP1-expressed lymphoma. Leukemia & Lymphoma 2019, 60:5, 1193-1203. (IF: 2.674, 5-Year IF: 2.418, ranking: 40/73 (54.8 %) in Hematology)
  18. Chen YF, Chen GY, Chang CH, Su YC, Chen YC, Jiang YS, Jan JS. TRAIL encapsulated to polypeptide-crosslinked nanogel exhibits increased anti-inflammatory activities in Klebsiella pneumoniae-induced sepsis treatment. Materials Science and Engineering C 2019, 102, 85-95. (IF: 5.08, 5-Year IF: 4.628, ranking: 6/33 (18.2%) in Materials Science, Biomaterials)
  19. Chen YF, Chang CH, Lin CY, Lin LF, Yeh ML, Jan JS. Disulfide-cross-linked PEG-block-polypeptide nanoparticles with high drug loading content as glutathione-triggered anticancer drug nanocarriers. Colloids Surf B Biointerfaces 2018, 165:172-181. (IF: 3.887, 5-Year IF: 4.298, ranking: 16/72 (22.2%) in Biophysics)
  20. How SC, Chen YF, Hsieh PL, Wang SS, Jan JS. Cell-targeted, dual reduction- and pH-responsive saccharide/lipoic acid-modified poly(L-lysine) and poly(acrylic acid) polyionic complex nanogels for drug delivery. Colloids Surf B Biointerfaces 2017, 153:244-252. (IF: 3.887, 5-Year IF: 4.298, ranking: 16/72 (22.2%) in Biophysics)
  21. Chen YF, Shiau AL, Chang SJ, Fan NS, Wang CT, Wu CL, Jan JS. One-dimensional poly(L-lysine)-block-poly(L-threonine) assemblies exhibit potent anticancer activity by enhancing membranolysis. Acta Biomater 2017, 55:283-295. (IF: 6.319, 5-Year IF: 6.804, ranking: 3/77 (3.9%) in Engineering, Biomedical)
  22. Zhang YX, Chen YF, Shen YX, Hu JJ, Jan JS. Reduction- and pH-Sensitive lipoic acid-modified Poly(l-lysine) and polypeptide/silica hybrid hydrogels/nanogels. Polymer 2016, 86:32–41. (IF: 3.586, 5-Year IF: 3.775, ranking: 12/85 (14.1%) in Polymer Science)
  23. Huang CH, Chan YY, Kuo PC, Chen YF, Chang RJ, Chen IS, Wu SJ, Wu TS. The constituents of roots and stems of Illigera luzonensis and their anti-platelet aggregation effects. Int J Mol Sci 2014, 15:13424-13436. (IF: 2.339, 5-Year IF: 2.721, ranking: 52/148 (35%) in Chemistry, Multidisciplinary)
  24. Chen YF, Wang SH, Chang SJ, Shiau AL, Her LS, Shieh GS, et al. Zhankuic acid A as a novel JAK2 inhibitor for the treatment of Concanavalin A- induced hepatitis. Biochem Pharmacol 2014, 91:217-230. (IF: 4.65, 5-Year IF: 4.772, ranking: 25/256 (9.7%) in Pharmacology & Pharmacy)
  25. Chan YY, Juang SH, Huang GJ, Liao YR, Chen YF, Wu CC, et al. The constituents of Michelia compressa var. formosana and their bioactivities. Int J Mol Sci 2014, 15:10926-10935. (IF: 2.339, 5-Year IF: 2.721, ranking: 52/148 (35%) in Chemistry, Multidisciplinary)
  26. Chen YF, Shiau AL, Wang SH, Yang JS, Chang SJ, Wu CL, et al. Zhankuic acid A isolated from Taiwanofungus camphoratus is a novel selective TLR4/MD-2 antagonist with anti-inflammatory properties. J Immunol 2014,192:2778-2786. (IF: 5.362, 5-Year IF: 5.57, ranking: 24/144 (16.7%) in Immunology)
  27. Tsai YS, Shiau AL, Chen YF, Tsai HT, Tzai TS, Wu CL. Enhancement of antitumor activity of gammaretrovirus carrying IL-12 gene through genetic modification of envelope targeting HER2 receptor: a promising strategy for bladder cancer therapy. Cancer Gene Ther 2010,17:37-48. (IF: 3.126, 5-Year IF: 3.002, ranking: 43/152 (28%) in Biotechnology & Applied microbiology)
  28. Tsai YS, Shiau AL, Chen YF, Tsai HT, Lee HL, Tzai TS, et al. Enhancement of antitumor immune response by targeted interleukin-12 electrogene transfer through antiHER2 single-chain antibody in a murine bladder tumor model. Vaccine 2009,27:5383-5392. (IF: 3.298, 5-Year IF: 3.189, ranking: 19/83 (23%) in Medicine, Research & Experimental)
  29. Hsu KF, Wu CL, Huang SC, Hsieh JL, Huang YS, Chen YF, et al. Conditionally replicating E1B-deleted adenovirus driven by the squamous cell carcinoma antigen 2 promoter for uterine cervical cancer therapy. Cancer Gene Ther 2008,15:526-534. (IF: 3.889, 5-Year IF: 3.325, ranking: 24/138 (17%) in Biotechnology & Applied microbiology)
  30. Shih PC, Lee HH, Lai SC, Chen KM, Jiang ST, Chen YF, et al. Efficacy of curcumin therapy against Angiostrongylus cantonensis-induced eosinophilic meningitis. J Helminthol 2007,81:1-5. (IF: 0.779, ranking: 72/115 (63%) in Zoology)

 

研討會論文
  • 2024.1 ST Huang, Chen YF, Jan JS. Star-shaped poly(L-Lysine) blocked with L-alanine as a gene carrier for organoids. Annual Meeting of the Polymer Society. Cheng Kung University, Tainan, Taiwan. (the Excellence Award) 學術壁報論文優等獎，共同作者。
  • 2024.1 JQ Yang, Jan JS, Chen YF*. Crosslinking polyvinyl alcohol with natural aromatic aldehydes prepares antibacterial films. Annual Meeting of the Polymer Society. Cheng Kung University, Tainan, Taiwan. (the Honorable Mention Award) 學術壁報論文佳作獎，指導老師。
  • 2023.12 Shao JW, Chung FY, Jan JS, Chen YF*. DNA nanogels crosslinked with benzyl derivatives exhibit membranolytic antibacterial activity. 70th TwIChE Annual Meeting. National Taiwan University, Taipei, Taiwan. (the Honorable Mention Award) 學術壁報論文佳作獎，指導老師。
  • 2023.12 Chen HJ, Yang JQ, Jan JS, Chen YF*. Crosslinking kiwifruit-derived DNA with aromatic aldehydes to prepare antibacterial nanogels. 70th TwIChE Annual Meeting. National Taiwan University, Taipei, Taiwan.
  • 2023.7 Chung FY, Huang CR, Chen YF*. Application of nucleic acids in antibacterial materials, International Conference on Biomaterials Science and Tissue Engineering, Osaka, Japan.
  • 2023.1 Chung FY, Huang CR, Jan JS, Chen YF*.  Chemical-modified natural nanogels crosslinked with S-Benzyl-L-cysteine exhibit potent antibacterial activity, Annual Meeting of the Polymer Society. Chang Gung University, Taoyuan, Taiwan. (the High Distinction Award) 學術壁報論文特優獎，指導老師。
  • 2023.1 Yang JQ, YC Chu, Jan JS and Chen YF*. Evaluation of antimicrobial efficacy of crosslinked polymers synthesized from natural aldehydes and kiwifruit-derived nucleic acid, Annual Meeting of the Polymer Society. Chang Gung University, Taoyuan, Taiwan.
  • 2022.12 Yang JQ, Jan JS and Chen YF*. Antibacterial effects of natural aldehyde cross-linked DNA nanogels. 69th TwIChE Annual Meeting. Tamkang University, Taipei, Taiwan.
  • 2022.12 Chung FY, Huang CR, Jan JS, Chen YF*. S-Benzyl-L-cysteine modified natural nanogels exhibit potent antibacterial activity. 69th TwIChE Annual Meeting. Tamkang University, Taipei, Taiwan. (the Honorable Mention Award) 學術壁報論文佳作獎，指導老師。
  • 2022.12 Lin JR, Chang HJ, Chen YF, Chang CH. Modulation for thermosensitive characteristics of negatively charged catanionic vesicles fabricated from a mixed pseudotriple-chained ion pair amphiphile/cholesterol system. 69th TwIChE Annual Meeting. Tamkang University, Taipei, Taiwan.
  • 2022.12 Lin WL, Liao CT, Mravec F, Chen YF, Chang CH. Characteristics of complexes fabricated from positively charged catanionic vesicles with hyaluronic acid: encapsulation efficiency and cell viability. 69th TwIChE Annual Meeting. Tamkang University, Taipei, Taiwan.
  • 2022.7 Lin YZ, Huang GW, Jan JS, Chen YF*. Evaluation of antimicrobial efficacy of cross-linked polymers synthesized from natural aldehydes and plant nucleic acids. International Conference on Precision Nanomedicine in Theranostics & The 2022 Annual Meeting of Taiwan Nanomedicine Society. Sheraton Hsinchu Hotel, Hsinchu, Taiwan.
  • 2022.7 Chung FY, Huang CR, Jan JS, Chen YF*. Natural nanogels crosslinked with S-Benzyl-L-cysteine exhibit potent antibacterial activity. International Conference on Precision Nanomedicine in Theranostics & The 2022 Annual Meeting of Taiwan Nanomedicine Society. Sheraton Hsinchu Hotel, Hsinchu, Taiwan.
  • 2022.1   Tsai YJ, Chen YF and Jan JS. Synthesis of cationic polypeptide dendrimers for gene delivery, 2022 International Conference on Modern Challenges in Polymer Science and Technology. National Chin-Yi University of Technology, Taichung, Taiwan. (the Excellence Award) 學術壁報論文優等獎，共同作者。
  • 2021.12   Jiang YS, Chu YC, Jan JS, and Chen YF*. ZnO-loaded DNA nanogels as neutrophil extracellular trap-like structures in the treatment of mouse peritonitis, Annual Meeting of Biomaterials and Controlled Release Society in Taiwan. National Cheng Kung University, Tainan, Taiwan.
  • 2021.10   Chu YC, Su RT, Chiu HY and Chen YF*. Neutrophil extracellular trap-like structures as a strategy for the treatment of peritonitis, International Conference on Precision Nanomedicine in Theranostics & The 2021 Annual Meeting of Taiwan Nanomedicine Society. Sheraton Tainan Hotel, Tainan, Taiwan.
  • 2020.10   Weng SM, Chen YF, Jan JS. DNA-based Nanogels for payload encapsulation, 67th TwIChE Annual Meeting. National Tsing Hua University, Hsinchu, Taiwan.
  • 2020.7   Chang HM, Weng SM, Chen YF, Chang CH. DNA-based nanocarrier for anticancer drug encapsulation, Annual Conference of the Republic of China Interface Science Society and the Science and Technology Department's Chemical Science Achievements Presentation Conference. National Taiwan University of Science and Technology, Taipei, Taiwan.
  • 2019. 11   Huang PS, Chen KC, Chen YF, Chang CH. Physicochemical properties and vitamin E acetate encapsulation efficiency of catanionic vesicles fabricated from triplechained ion pair amphiphile. 66th TwIChE Annual Meeting. Tunghai University, Taichung, Taiwan. (the Excellence Award) 學術壁報論文優等獎，共同作者。
  • 2019.11   Lin KY, Lin YS, Chen YF, PJ Tsai, Jan JS, IH Huang. Development of a polyvalent mucosal vaccine against Clostridium difficile infection. The Chinese Society of Immunology. National Taiwan University, Taipei, Taiwan. (the Excellence Award) 學術壁報論文優等獎，共同作者。
  • 2019.7   Chen YF, Chen KC, Huang PS, Chang CH. Cholesterol content enhances gene delivery efficiency in catanionic vesicles, 2019 Annual Conference of the Republic of China Interface Science Society and the Science and Technology Department's Chemical Science Achievements Presentation Conference. Kaohsiung University of Science and Technology, Kaohsiung, Taiwan.
  • 2019.7   Huang PS, Chen YF, Mravec F, Chang CH. Exploring physical properties of charged catanionic vesicle/hyaluronic acid complexes. 2019 Annual Conference of the Republic of China Interface Science Society and the Science and Technology Department's Chemical Science Achievements Presentation Conference. Kaohsiung University of Science and Technology, Kaohsiung, Taiwan.
  • 2019.7   Chen YP, Lin YC, Chen YF, Chang CH. Development of drug delivery carriers from microalgal lipids. 2019 Annual Conference of the Republic of China Interface Science Society and the Science and Technology Department's Chemical Science Achievements Presentation Conference. Kaohsiung University of Science and Technology, Kaohsiung, Taiwan.
  • 2018.11   Chang CC, Su PH, Chen YF, Chang CH. Fabrication of Vesicular Structure from Pseudotriple-Chain Ion Pair Amphiphile. The 25th Regional Symposium of Chemical Engineering (RSCE 2018). De La Salle University, Makati City, Philippines.
  • 2018.6   Chen YF. The JAK inhibitor antcin H exhibits direct anti-cancer activity while enhancing chemotherapy against LMP1-expressed lymphoma, International Symposium on Taiwan Medicinal mushrooms: Antrodia cinnamomea, National Taitung University, Taitung, Taiwan. (the Second Place) 學術壁報論文貳獎，第一作者。
  • 2016.5   Chen YF, Wu CL, Shiau AL. Zhankuic acid A as a novel JAK2 inhibitor for the treatment of Concanavalin A- induced hepatitis, International Symposium and Workshop on Taiwan Medicinal mushrooms: Antrodia cinnamomea, Academia Sinica, Taipei, Taiwan. (the First Place) 學術壁報論文首獎，第一作者。
  • 2014.5   Chen YF, Wu CL, Shiau AL, Wu TS. Zhankuic acid A isolated from Taiwanofungus camphoratus is a novel selective TLR4/MD-2 antagonist with anti-inflammatory properties, International Symposium and Workshop on Taiwan Medicinal mushrooms: Antrodia cinnamomea, Academia Sinica, Taipei, Taiwan. (the Special Award) 學術壁報論文特別獎，第一作者。

指導學生得獎
  • 2024.2 3-Aminophenylboronic acid-modified nanocellulose crosslinked with disulfide to prepare DNA hybrid nanogels for anticancer drug carriers, Taiwan International Science Fair, Taipei, Taiwan. (Third Prize)三等獎. The work will be exhibited in Barcelona representing Taiwan.
  • 2023.4  Disulfide Cross-linked Nucleic Acids for Cancer Drug Applications. National Primary and High School Science Fair, Senior High School-Chemistry, Tainan, Taiwan (the High Distinction Award)特優
  • 2022.5   Development of genetically modified algae for reducing microplastics, Living Lab Project Awards, CTCI Education Foundation and Taiwan Institute for Sustainable Energy, Taipei, Taiwan (Honorable Mention)佳作
  • 2019.10   NCKU-ONA: DNA nanoparticles (ONA) serving as amphipathic carrier, Biomod Jamboree, San Francisco, CA, USA (Sliver Project Award)銀牌獎
  • 2019.2   Plant nucleic acids nanoparticles by disulfide-cross-linking as glutathione-triggered anticancer drug carriers, Taiwan International Science Fair, Taipei, Taiwan. (Third Prize)三等獎
  • 2017.11   Design peptide-based nanoparticles to compete mRNA binding site of human antigen R, Biomod Jamboree, San Francisco, CA, USA (Gold Project Award; Presentation 1st Place; Audience Choice 1st Place; Project Video 2nd Place)金牌獎

研究計畫
  1. 國科會專題研究計畫，主持人：開發以核酸為主的奈米材料作為抗藥性菌株的新型抗生素(2/2) (NSTC 112-2635-E-143-001)，112/08/01~113/07/31，台幣1,450,000元。
  2. 國科會專題研究計畫，共同主持人：線性與星狀聚胺酸高分子接枝不同天然醛類之抗癌活性與腸道菌相影響探討(NSTC 112-2221-E-006 -011 -MY3)，112/08/01~115/07/31，台幣3,900,000元。
  3. 科技部專題研究計畫，主持人：開發以核酸為主的奈米材料作為抗藥性菌株的新型抗生素(1/2) (MOST 111-2635-E-143-001), 2022/08/01~2023/07/31, 台幣 1,500,000元。
  4. 科技部專題研究計畫，共同主持人：評估聚胺酸嵌段高分子之癌症治療效果與腸道菌相影響 (MOST 110-2221-E-006 -002 -MY3),  2021/08/01~2024/07/31, 台幣 4,011,000元。

擔任期刊編輯委員會成員 (Editorial board member)

  1. International Journal of Agriculture, Engineering Technology and Social Sciences https://ijaetss.org/editorial-board/
  2. Frontiers in Bioengineering and Biotechnology https://loop.frontiersin.org/people/1963397/bio?fbclid=IwAR3oW39b5ECHl2Qi7C6emuqUzLKLL4l2fU74FR-K10rJs9dgq0OYY1J-fz8
  3. American Journal of Polymer Science and Technology (AJPST) http://www.ajpst.org/editorialboard

Patents

  US20150374718A1 Zhankuic Acid A and Analogs thereof and Their Use as an Anti-Inflammatory Agent

  US20150306112A1 Zhankuic acid A, a JAK2/3 tyrosine kinase inhibitor, and a potential therapeutic agent for hepatitis

  I713822 AMPHIPHILIC BLOCK COPOLYMER, NANOPARTICLE CONTAINING THE SAME, MEDICINAL COMPOSITION THEREOF AND METHOD OF INHIBITING RIBONUCLEIC ACID BINDING TO HUMAN ANTIGEN R USING THE SAME

  I815023 COMPOSITION FOR DELIVERY OF A BIOACTIVE AGENT AND METHOD OF MANUFACTURE AND USE THEREOF

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